Phosphorus oxychloride → Methyl 2-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]benzimidazole-7-carboxylate

HRID 959888Notes

Reaction equation

HRID 959888 reaction equation
[C:1](#[N:2])[c:3]1[c:4](-[c:9]2[cH:10][cH:11][c:12]([CH2:15][n:16]3[c:17](=[O:29])[nH:18][c:19]4[c:20]3[c:21]([C:25](=[O:26])[O:27][CH3:28])[cH:22][cH:23][cH:24]4)[cH:13][cH:14]2)[cH:5][cH:6][cH:7][cH:8]1.[P:30]([Cl:31])([Cl:32])([Cl:33])=[O:34]>>[C:1](#[N:2])[c:3]1[c:4](-[c:9]2[cH:10][cH:11][c:12]([CH2:15][n:16]3[c:17]([Cl:32])[n:18][c:19]4[c:20]3[c:21]([C:25](=[O:26])[O:27][CH3:28])[cH:22][cH:23][cH:24]4)[cH:13][cH:14]2)[cH:5][cH:6][cH:7][cH:8]1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 15654691Methyl 3-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate

Product 1

HCID 15654692Methyl 2-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]benzimidazole-7-carboxylate

Sources & evidence

ORD record
ord-1a01679a585846939b4bc2d3d71796d3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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