Dichloromethane → tert-butyl N-[1-[2-[[2-(difluoromethyl)-1-[(1-hept-6-enylcyclopropyl)sulfonylcarbamoyl]cyclopropyl]carbamoyl]-4-(4-phenylphenyl)-4-prop-2-enylsulfanylpyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
Reaction equation
[CH2:1]([CH:2]=[CH2:3])[S:4][C:5]1([c:28]2[cH:29][cH:30][c:31](-[c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)[cH:32][cH:33]2)[CH2:6][CH:7]([C:25](=[O:26])[OH:27])[N:8]([C:10]([CH:11]([C:12]([CH3:13])([CH3:14])[CH3:15])[NH:16][C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:9]1.[CH:87]([N:88]([CH2:89][CH3:90])[CH:91]([CH3:92])[CH3:93])([CH3:94])[CH3:95].[Cl:96][CH2:97][Cl:98].[NH2:40][C:41]1([C:47](=[O:48])[NH:49][S:50](=[O:51])(=[O:52])[C:53]2([CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH:61]=[CH2:62])[CH2:54][CH2:55]2)[CH:42]([CH:44]([F:45])[F:46])[CH2:43]1.[P-:63]([F:64])([F:65])([F:66])([F:67])([F:68])[F:69].[n:70]1([O:71][C:72]([N:73]([CH3:74])[CH3:75])=[N+:76]([CH3:77])[CH3:78])[c:79]2[n:80][cH:81][cH:82][cH:83][c:84]2[n:85][n:86]1>>[CH2:1]([CH:2]=[CH2:3])[S:4][C:5]1([c:28]2[cH:29][cH:30][c:31](-[c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)[cH:32][cH:33]2)[CH2:6][CH:7]([C:25](=[O:27])[NH:40][C:41]2([C:47](=[O:48])[NH:49][S:50](=[O:51])(=[O:52])[C:53]3([CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH:61]=[CH2:62])[CH2:54][CH2:55]3)[CH:42]([CH:44]([F:45])[F:46])[CH2:43]2)[N:8]([C:10]([CH:11]([C:12]([CH3:13])([CH3:14])[CH3:15])[NH:16][C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-6d70dc5b693c4716a4469ab08b038fe3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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