Pyrrolidine → [2-(4-methoxy-7-morpholin-4-yl-1,3-benzothiazol-2-yl)-4,5,7,8-tetrahydro-1H-imidazo[4,5-d]azepin-6-yl]-[2-(pyrrolidin-1-ylmethyl)-4-pyridinyl]methanone
Reaction equation
[CH2:38]1[CH2:39][CH2:40][NH:41][CH2:42]1.[Cl:1][CH2:2][c:3]1[n:4][cH:5][cH:6][c:7]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][c:14]3[c:15]([n:18][c:19](-[c:21]4[s:22][c:23]5[c:24]([n:25]4)[c:26]([O:36][CH3:37])[cH:27][cH:28][c:29]5[N:30]4[CH2:31][CH2:32][O:33][CH2:34][CH2:35]4)[nH:20]3)[CH2:16][CH2:17]2)[cH:8]1>>[CH2:2]([c:3]1[n:4][cH:5][cH:6][c:7]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][c:14]3[c:15]([nH:18][c:19](-[c:21]4[s:22][c:23]5[c:24]([n:25]4)[c:26]([O:36][CH3:37])[cH:27][cH:28][c:29]5[N:30]4[CH2:31][CH2:32][O:33][CH2:34][CH2:35]4)[n:20]3)[CH2:16][CH2:17]2)[cH:8]1)[N:41]1[CH2:40][CH2:39][CH2:38][CH2:42]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8bb3940fd7bd4d0c8de8f7307aa2a2bb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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