Hydrochloric Acid → 6-[[2-(1-methylpyrazol-4-yl)-4-pyridinyl]oxy]-N-piperidin-3-yl-1,3-benzothiazol-2-amine

HRID 960086Notes

Reaction equation

[CH3:1][n:2]1[n:3][cH:4][c:5](-[c:7]2[n:8][cH:9][cH:10][c:11]([O:13][c:14]3[cH:15][c:16]4[c:17]([n:18][c:19]([NH:21][CH:22]5[CH2:23][N:24]([C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[CH2:25][CH2:26][CH2:27]5)[s:20]4)[cH:35][cH:36]3)[cH:12]2)[cH:6]1.[ClH:43].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1>>[CH3:1][n:2]1[n:3][cH:4][c:5](-[c:7]2[n:8][cH:9][cH:10][c:11]([O:13][c:14]3[cH:15][c:16]4[c:17]([n:18][c:19]([NH:21][CH:22]5[CH2:23][NH:24][CH2:25][CH2:26][CH2:27]5)[s:20]4)[cH:35][cH:36]3)[cH:12]2)[cH:6]1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 312751,4-Dioxane

HCID 87421254Tert-butyl 3-[[6-[[2-(1-methylpyrazol-4-yl)-4-pyridinyl]oxy]-1,3-benzothiazol-2-yl]amino]piperidine-1-carboxylate

Product 1

HCID 874213196-[[2-(1-methylpyrazol-4-yl)-4-pyridinyl]oxy]-N-piperidin-3-yl-1,3-benzothiazol-2-amine

Sources & evidence

ORD record: ord-1b216deeed0d4d0a87e0ce2e6d5c7198
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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