Dimethylformamide → N-(5'-bromo-5-fluoro-3,4'-bipyridin-2'-yl)-N'-ethylurea

HRID 960117Notes

Reaction equation

HRID 960117 reaction equation
[Br:20][NH:21][C:22](=[O:23])[CH2:24][CH2:25][C:26]([NH2:27])=[O:28].[CH2:1]([CH3:2])[NH:3][C:4](=[O:5])[NH:6][c:7]1[n:8][cH:9][cH:10][c:11](-[c:13]2[cH:14][n:15][cH:16][c:17]([F:19])[cH:18]2)[cH:12]1.[O:29]=[CH:30][N:31]([CH3:32])[CH3:33]>>[CH2:1]([CH3:2])[NH:3][C:4](=[O:5])[NH:6][c:7]1[n:8][cH:9][c:10]([Br:20])[c:11](-[c:13]2[cH:14][n:15][cH:16][c:17]([F:19])[cH:18]2)[cH:12]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 9834204N-BromosuccinamideHCID 59208495HCID 59208495, compound

Product 1

HCID 59208332N-(5'-bromo-5-fluoro-3,4'-bipyridin-2'-yl)-N'-ethylurea

Sources & evidence

ORD record
ord-bbc5478ae4864ea1a93893340aedfb0d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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