Acetate → 5-(2,4-difluorophenoxy)-1-(2-fluoro-2-methylpropyl)-1H-indazole-6-carboxylic acid

HRID 960120Notes

Reaction equation

[Br:1][c:2]1[c:3]([O:16][c:17]2[c:18]([F:24])[cH:19][c:20]([F:23])[cH:21][cH:22]2)[cH:4][c:5]2[cH:6][n:7][n:8]([CH2:11][C:12]([CH3:13])([CH3:14])[F:15])[c:9]2[cH:10]1.[C:54]([O-:55])([O-:56])=[O:57].[CH3:62][OH:63].[ClH:60].[K+:58].[K+:59].[O-:65][C:66]([CH3:67])=[O:68].[O-:69][C:70]([CH3:71])=[O:72].[OH2:61].[Pd+2:64].[c:25]1([P:26]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[CH2:33][CH2:34][CH2:35][P:36]([c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[cH:49][cH:50][cH:51][cH:52][cH:53]1>>[c:2]1([C:54](=[O:55])[OH:56])[c:3]([O:16][c:17]2[c:18]([F:24])[cH:19][c:20]([F:23])[cH:21][cH:22]2)[cH:4][c:5]2[cH:6][n:7][n:8]([CH2:11][C:12]([CH3:13])([CH3:14])[F:15])[c:9]2[cH:10]1