2-Bromoethanol → 2-(1-(2-hydroxyethyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide
Reaction equation
[Br:13][CH2:14][CH2:15][OH:16].[CH3:17][c:18]1[n:19][c:20](-[n:33]2[cH:34][n:35][nH:36][c:37]2=[O:38])[s:21][c:22]1[C:23](=[O:24])[NH:25][CH2:26][c:27]1[cH:28][n:29][cH:30][cH:31][cH:32]1.[F:1][C:2]([F:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:9][Br:10])[cH:11][cH:12]1>>[CH2:14]([CH2:15][OH:16])[n:36]1[n:35][cH:34][n:33](-[c:20]2[n:19][c:18]([CH3:17])[c:22]([C:23](=[O:24])[NH:25][CH2:26][c:27]3[cH:28][n:29][cH:30][cH:31][cH:32]3)[s:21]2)[c:37]1=[O:38]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-709c8ef3c052481faf5e1389a6a1d382
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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