Dichloromethane → 7-chloro-6-[3-(3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-propylthio]-2,3,4,5-tetrahydro-1H-benzo[d]azepine
Reaction equation
[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH2:17][c:18]2[c:19]([c:22]([S:27][CH2:28][CH2:29][CH2:30][c:31]3[cH:32][c:33]4[c:37]([cH:38][cH:39]3)[NH:36][C:35](=[O:40])[C:34]4([CH3:41])[CH3:42])[c:23]([Cl:26])[cH:24][cH:25]2)[CH2:20][CH2:21]1)([CH3:12])([CH3:13])[CH3:14].[Cl:43][CH2:44][Cl:45].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][c:18]2[c:19]([c:22]([S:27][CH2:28][CH2:29][CH2:30][c:31]3[cH:32][c:33]4[c:37]([cH:38][cH:39]3)[NH:36][C:35](=[O:40])[C:34]4([CH3:41])[CH3:42])[c:23]([Cl:26])[cH:24][cH:25]2)[CH2:20][CH2:21]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7301001ba51148729e0ed6911470dabe
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…