Chloride → 1-Acetyl-4-(4-fluorobenzoyl)piperidine

HRID 960351Notes

Reaction equation

HRID 960351 reaction equation
[Al+3:14].[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][CH:7]([C:8](=[O:9])[Cl:10])[CH2:11][CH2:12]1.[Cl-:13].[Cl-:15].[Cl-:16].[F:17][c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][CH:7]([C:8](=[O:9])[c:21]2[cH:20][cH:19][c:18]([F:17])[cH:23][cH:22]2)[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 312Chloride3×HCID 10008FluorobenzeneHCID 1009501-Acetylpiperidine-4-carbonyl chlorideHCID 104727Aluminum Cation

Product 1

HCID 1172571-Acetyl-4-(4-fluorobenzoyl)piperidine

Sources & evidence

ORD record
ord-80ed62270b164d4c876227a27438733e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…