Cyclopropanecarbonyl chloride → {2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-6,5'-dimethoxy-biphenyl-3-yl}-acetic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:13]2[c:14]([CH2:21][NH:22][CH2:23][CH3:24])[cH:15][cH:16][c:17]([O:19][CH3:20])[cH:18]2)[c:8]([O:11][CH3:12])[cH:9][cH:10]1)=[O:25].[CH:26]1([C:29](=[O:30])[Cl:31])[CH2:27][CH2:28]1>>[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:13]2[c:14]([CH2:21][N:22]([CH2:23][CH3:24])[C:29]([CH:26]3[CH2:27][CH2:28]3)=[O:30])[cH:15][cH:16][c:17]([O:19][CH3:20])[cH:18]2)[c:8]([O:11][CH3:12])[cH:9][cH:10]1)=[O:25]Participants
3
Sources & evidence
- ORD record
- ord-d51615529ad344ef84f45ad404efdf2e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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