Hydrochloric Acid → 1-Benzyl-4-(4-methoxyphenyl)piperidine

HRID 960614Notes

Reaction equation

HRID 960614 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)=[CH:12][CH2:13]1.[CH3:26][OH:27].[ClH:24].[ClH:25].[H:22][H:23]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric Acid2×HCID 887MethanolHCID 106364031-Benzyl-4-(4-methoxyphenyl)-1,2,3,6-tetrahydropyridineHCID 178418361HCID 178418361, compound

Product 1

HCID 232889401-Benzyl-4-(4-methoxyphenyl)piperidine

Sources & evidence

ORD record
ord-3919f5b37f894af89b64a865d42d9fb8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…