Sodium ion → 1,1-Dimethylethyl 7-({5-[(methyloxy)carbonyl]-2-pyrazinyl}oxy)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate

HRID 960628Notes

Reaction equation

HRID 960628 reaction equation
[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][c:13]2[c:14]([cH:17][c:18]([OH:21])[cH:19][cH:20]2)[CH2:15][CH2:16]1.[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[Cl:22][c:23]1[n:24][cH:25][c:26]([C:29](=[O:30])[O:31][CH3:32])[n:27][cH:28]1.[H-:1].[Na+:2]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][c:13]2[c:14]([cH:17][c:18]([O:21][c:23]3[n:24][cH:25][c:26]([C:29](=[O:30])[O:31][CH3:32])[n:27][cH:28]3)[cH:19][cH:20]2)[CH2:15][CH2:16]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 406081Methyl 5-chloropyrazine-2-carboxylateHCID 18173274tert-butyl 7-hydroxy-2,3,4,5-tetrahydro-1H-3-benzazepine-3-carboxylate

Product 1

HCID 589845771,1-Dimethylethyl 7-({5-[(methyloxy)carbonyl]-2-pyrazinyl}oxy)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate

Sources & evidence

ORD record
ord-6adf3beaf8ec4b48a0aa42a5c3c465fa
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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