Borane → 1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-(3-fluorophenyl)piperidine
Reaction equation
[BH3:26].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[O:1]1[CH:2]([C:11](=[O:12])[N:13]2[CH2:14][CH:15]([c:19]3[cH:20][c:21]([F:25])[cH:22][cH:23][cH:24]3)[CH2:16][CH2:17][CH2:18]2)[CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2>>[O:1]1[CH:2]([CH2:11][N:13]2[CH2:14][CH:15]([c:19]3[cH:20][c:21]([F:25])[cH:22][cH:23][cH:24]3)[CH2:16][CH2:17][CH2:18]2)[CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2Participants
4
Sources & evidence
- ORD record
- ord-c0a382a326824a3a9d807071675dd9c7
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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