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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 960853Generated: October 30, 2026

1-(Bromomethyl)-4-(trifluoromethyl)benzene → ethyl 2-(1-(4-(difluoromethoxy)benzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methylthiazole-5-carboxylate

https://huagongshe.com/reaction/960853

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-4-(trifluoromethyl)benzeneHCID 123062—
Reactant4-(Difluoromethoxy)benzyl BromideHCID 2737001—
Reactantethyl 4-methyl-2-(5-oxo-1H-1,2,4-triazol-4(5H)-yl)thiazole-5-carboxylateHCID 57920013—
Productethyl 2-(1-(4-(difluoromethoxy)benzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methylthiazole-5-carboxylateHCID 58031580—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-0341690d08df4ca9978fe534f4bb9e63
Source noteValidation data from https://doi.org/10.1039/C8SC04228D