Chloride → Tert-butyl 4-formyl-2-pyridin-3-yl-1,3-thiazolidine-3-carboxylate

HRID 960917Notes

Reaction equation

HRID 960917 reaction equation
[CH2:24]([Al+:25][CH2:26][CH:27]([CH3:28])[CH3:29])[CH:30]([CH3:31])[CH3:32].[CH2:37]([Cl:38])[Cl:39].[Cl-:34].[H-:23].[Na+:33].[Na+:36].[OH-:35].[n:1]1[cH:2][c:3]([CH:7]2[S:8][CH2:9][CH:10]([C:19](=[O:20])[O:21][CH3:22])[N:11]2[C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3]([CH:7]2[S:8][CH2:9][CH:10]([CH:19]=[O:20])[N:11]2[C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[cH:4][cH:5][cH:6]1

Participants

8

Reactant 7

HCID 312ChlorideHCID 923Sodium ion2×HCID 961HydroxideHCID 6344DichloromethaneHCID 166653HydrideHCID 16686348Bis(2-methylpropyl)alumanyliumHCID 20097554Methyl-2-(3-pyridinyl)-3-tert-butoxycarbonyl-4-thiazolidinecarboxylate

Product 1

HCID 20097598Tert-butyl 4-formyl-2-pyridin-3-yl-1,3-thiazolidine-3-carboxylate

Sources & evidence

ORD record
ord-72209cfc745c4a9a9f4ddbceaafcc15d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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