Acetate → 4-Cyclopropyl-2-nitroaniline

HRID 960945Notes

Reaction equation

HRID 960945 reaction equation
[Br:1][c:2]1[cH:3][c:4]([N+:9](=[O:10])[O-:11])[c:5]([NH2:6])[cH:7][cH:8]1.[CH3:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[CH:12]1([B:15]([OH:16])[OH:17])[CH2:13][CH2:14]1.[CH:26]1([PH2:27])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]1.[Cl:50][CH2:51][Cl:52].[K+:23].[K+:24].[K+:25].[O-:41][C:42]([CH3:43])=[O:44].[O-:45][C:46]([CH3:47])=[O:48].[OH2:49].[P:18]([O-:19])([O-:20])([O-:21])=[O:22].[Pd+2:40]>>[c:2]1([CH:12]2[CH2:13][CH2:14]2)[cH:3][c:4]([N+:9](=[O:10])[O-:11])[c:5]([NH2:6])[cH:7][cH:8]1

Participants

11

Reactant 10

HCID 175Acetate2×HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 1140TolueneHCID 6344DichloromethaneHCID 13199CyclohexylphosphineHCID 701324-Bromo-2-nitroanilineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2760897Cyclopropylboronic acid

Product 1

HCID 222249274-Cyclopropyl-2-nitroaniline

Sources & evidence

ORD record
ord-a4a02ddabcac4f559079d87382f32ed3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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