Acetonitrile → (4-Amino-3-chloro-phenyl)-acetic acid ethyl ester

HRID 961050Notes

Reaction equation

HRID 961050 reaction equation
[CH2:9]([CH3:10])[O:11][C:12]([CH2:13][c:14]1[cH:15][cH:16][c:17]([NH2:20])[cH:18][cH:19]1)=[O:21].[CH3:22][C:23]#[N:24].[Cl:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8]>>[Cl:1][c:18]1[c:17]([NH2:20])[cH:16][cH:15][c:14]([CH2:13][C:12]([O:11][CH2:9][CH3:10])=[O:21])[cH:19]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 31398ChlorosuccinimideHCID 225219p-Aminophenylacetic acid ethyl ester

Product 1

HCID 17859298(4-Amino-3-chloro-phenyl)-acetic acid ethyl ester

Sources & evidence

ORD record
ord-367a9b1d75ce4a16bafbc80ae6d97075
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…