Methanol → 4-(trans-4-Hydroxycyclohexyl)-1-methylpiperazin-2-one
Reaction equation
[CH3:1][N:2]1[C:3](=[O:15])[CH2:4][N:5]([CH:8]2[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]2)[CH2:6][CH2:7]1.[CH3:21][OH:22].[O:16]1[CH2:17][CH2:18][CH2:19][CH2:20]1>>[CH3:1][N:2]1[C:3](=[O:15])[CH2:4][N:5]([CH:8]2[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]2)[CH2:6][CH2:7]1Participants
4
Sources & evidence
- ORD record
- ord-25b2bd4b296b435daaa0dfef9829ec6c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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