Bicarbonate Ion → 4-(2,3-Dichlorobenzoyl)piperazin-2-one

HRID 961156Notes

Reaction equation

HRID 961156 reaction equation
[CH3:8][CH2:9][N:10]([CH2:11][CH3:12])[CH2:13][CH3:14].[Cl:15][c:16]1[c:17]([C:18](=[O:19])[Cl:20])[cH:21][cH:22][cH:23][c:24]1[Cl:25].[Cl:26][CH2:27][Cl:28].[NH:1]1[C:2](=[O:7])[CH2:3][NH:4][CH2:5][CH2:6]1.[Na+:33].[O-:29][C:30]([OH:31])=[O:32]>>[NH:1]1[C:2](=[O:7])[CH2:3][N:4]([C:18]([c:17]2[c:16]([Cl:15])[c:24]([Cl:25])[cH:23][cH:22][cH:21]2)=[O:19])[CH2:5][CH2:6]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6344DichloromethaneHCID 8471TriethylamineHCID 179442,3-Dichlorobenzoyl chlorideHCID 231360Piperazin-2-one

Product 1

HCID 310960434-(2,3-Dichlorobenzoyl)piperazin-2-one

Sources & evidence

ORD record
ord-985c9bbd5ed8480d86fe160d7884400f
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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