Hydrochloric Acid → tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate

HRID 961393Notes

Reaction equation

HRID 961393 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([N+:20]([O-:21])=[O:22])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[CH3:24][OH:25].[Cl:26][CH2:27][Cl:28].[ClH:23]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([NH2:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 6344DichloromethaneHCID 33806961-Boc-4-(4-Nitrophenyl)piperazine

Product 1

HCID 11011301tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-8bfa98d2e1de41479c22450fa6980408
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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