Acetic Acid → Tert-butyl 4-{4-amino-5-[3-fluoro-4-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl}piperidine-1-carboxylate

HRID 961418Notes

Reaction equation

[CH3:53][C:54](=[O:55])[OH:56].[N:1]#[N:2].[NH2:3][c:4]1[n:5][cH:6][n:7][n:8]2[c:9]1[c:10](-[c:29]1[cH:30][c:31]([F:50])[c:32]([NH:35][C:36]([NH:37][c:38]3[c:39]([F:48])[cH:40][cH:41][c:42]([C:44]([F:45])([F:46])[F:47])[cH:43]3)=[O:49])[cH:33][cH:34]1)[c:11]([CH2:26][O:27][CH3:28])[c:12]2[C:13]1=[CH:18][CH2:17][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:15][CH2:14]1.[Pt:51]=[O:52]>>[NH2:3][c:4]1[n:5][cH:6][n:7][n:8]2[c:9]1[c:10](-[c:29]1[cH:30][c:31]([F:50])[c:32]([NH:35][C:36]([NH:37][c:38]3[c:39]([F:48])[cH:40][cH:41][c:42]([C:44]([F:45])([F:46])[F:47])[cH:43]3)=[O:49])[cH:33][cH:34]1)[c:11]([CH2:26][O:27][CH3:28])[c:12]2[CH:13]1[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]1