Water → (4-Nitrophenyl) 4-(1,3,3a,4,7,7a-hexahydroisoindol-2-yl)-2-[(4-methylphenyl)methyl]-4-oxobutanoate

HRID 961534Notes

Reaction equation

HRID 961534 reaction equation
[CH2:35]1[NH:36][CH2:37][CH:38]2[CH2:39][CH:40]=[CH:41][CH2:42][CH:43]12.[CH3:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]([C:8](=[O:9])[O:10][c:11]2[cH:12][cH:13][c:14]([N+:17](=[O:18])[O-:19])[cH:15][cH:16]2)[CH2:20][C:21]([O:23][c:22]2[cH:24][cH:25][c:26]([N+:27]([O-:28])=[O:29])[cH:30][cH:31]2)=[O:32])[cH:33][cH:34]1.[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[OH2:44]>>[CH3:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]([C:8](=[O:9])[O:10][c:11]2[cH:12][cH:13][c:14]([N+:17](=[O:18])[O-:19])[cH:15][cH:16]2)[CH2:20][C:21](=[O:23])[N:36]2[CH2:35][CH:43]3[CH:38]([CH2:37]2)[CH2:39][CH:40]=[CH:41][CH2:42]3)[cH:33][cH:34]1

Participants

5

Reactant 4

HCID 962WaterHCID 6228DimethylformamideHCID 205218632,3,3a,4,7,7a-Hexahydro-1H-isoindoleHCID 54101102Di(4-nitrophenyl) 2-(4-methylbenzyl)succinate

Product 1

HCID 19769753(4-Nitrophenyl) 4-(1,3,3a,4,7,7a-hexahydroisoindol-2-yl)-2-[(4-methylphenyl)methyl]-4-oxobutanoate

Sources & evidence

ORD record
ord-9aa4447f4a3c4923b16c367572ca312a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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