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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 961773Generated: October 30, 2026

1-(4-(6-(4-Methoxybenzylamino)pyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea → tert-butyl N-[1-[3-[4-[2-fluoro-4-[[2-(4-fluorophenyl)acetyl]carbamoylamino]phenoxy]-3-pyridinyl]prop-2-enoyl]piperidin-4-yl]carbamate

https://huagongshe.com/reaction/961773

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-(6-(4-Methoxybenzylamino)pyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)ureaHCID 11569893—
Reactant2-(4-Fluorophenyl)acetyl isocyanateHCID 23153088—
Reactanttert-butyl N-[1-[3-[4-(4-amino-2-fluorophenoxy)-3-pyridinyl]prop-2-enoyl]piperidin-4-yl]carbamateHCID 66917613—
Producttert-butyl N-[1-[3-[4-[2-fluoro-4-[[2-(4-fluorophenyl)acetyl]carbamoylamino]phenoxy]-3-pyridinyl]prop-2-enoyl]piperidin-4-yl]carbamateHCID 72578595—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-72282b4fcc894e058cec61dc3fbccfca
Source noteValidation data from https://doi.org/10.1039/C8SC04228D