Sodium ion → N-(5-Hydroxymethyl-2-methylphenyl)-N-(3-methoxypropyl)acetamide

HRID 961813Notes

Reaction equation

HRID 961813 reaction equation
[CH3:24][N:25]([CH3:26])[CH:27]=[O:28].[Cl:16][CH2:17][CH2:18][CH2:19][O:20][CH3:21].[H-:14].[I-:23].[Na+:15].[Na+:22].[OH:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([CH3:13])[c:7]([NH:9][C:10]([CH3:11])=[O:12])[cH:8]1>>[OH:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([CH3:13])[c:7]([N:9]([C:10]([CH3:11])=[O:12])[CH2:17][CH2:18][CH2:19][O:20][CH3:21])[cH:8]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 30165Iodide IonHCID 1189271-Chloro-3-methoxypropaneHCID 166653HydrideHCID 14543056N-[5-(Hydroxymethyl)-2-methylphenyl]acetamide

Product 1

HCID 68506164N-(5-Hydroxymethyl-2-methylphenyl)-N-(3-methoxypropyl)acetamide

Sources & evidence

ORD record
ord-a098a66715454fd5bcf577a9d0e3c6bd
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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