Dichloromethane → 2-[2-[[2-(4-Chlorophenyl)-4-methylthiazole-5-carbonyl]aminomethyl]morpholin-4-yl]benzoic acid
Reaction equation
[Cl:44][CH2:45][Cl:46].[Cl:8][c:9]1[cH:10][cH:11][c:12](-[c:15]2[s:16][c:17]([C:21](=[O:22])[NH:23][CH2:24][CH:25]3[O:26][CH2:27][CH2:28][N:29]([c:31]4[c:32]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[cH:40][cH:41][cH:42][cH:43]4)[CH2:30]3)[c:18]([CH3:20])[n:19]2)[cH:13][cH:14]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[Cl:8][c:9]1[cH:10][cH:11][c:12](-[c:15]2[s:16][c:17]([C:21](=[O:22])[NH:23][CH2:24][CH:25]3[O:26][CH2:27][CH2:28][N:29]([c:31]4[c:32]([C:33](=[O:34])[OH:35])[cH:40][cH:41][cH:42][cH:43]4)[CH2:30]3)[c:18]([CH3:20])[n:19]2)[cH:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-b9cb2501ecfc4f82ad8a314e1e0d71c3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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