Piperidine → 6-tert-Butyl-2-piperidin-1-ylnicotinonitrile
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]([Cl:13])[c:8]([C:9]#[N:10])[cH:11][cH:12]1.[CH2:14]1[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][c:7]([N:17]2[CH2:16][CH2:15][CH2:14][CH2:19][CH2:18]2)[c:8]([C:9]#[N:10])[cH:11][cH:12]1Participants
3
Sources & evidence
- ORD record
- ord-26cf986bd23544a5b6d85461002ef797
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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