Dichloromethane → N-benzyl-2-(tert-butoxycarbonylamino)-5-indan carboxamide

HRID 962074Notes

Reaction equation

HRID 962074 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][c:11]2[cH:12][cH:13][c:14]([C:18](=[O:19])[OH:20])[cH:15][c:16]2[CH2:17]1.[CH2:36]([P:37]([OH:38])([OH:39])=[O:40])[CH2:41][CH3:42].[CH2:52]([Cl:53])[Cl:54].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[CH3:43][N:44]([c:45]1[cH:46][cH:47][cH:48][cH:49][n:50]1)[CH3:51].[NH2:21][CH2:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][c:11]2[cH:12][cH:13][c:14]([C:18](=[O:20])[NH:21][CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[cH:15][c:16]2[CH2:17]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 7504BenzylamineHCID 8471TriethylamineHCID 218852-DimethylaminopyridineHCID 204484Propylphosphonic acidHCID 227195982-((tert-butoxycarbonyl)amino)-2,3-dihydro-1H-indene-5-carboxylic acid

Product 1

HCID 22719645N-benzyl-2-(tert-butoxycarbonylamino)-5-indan carboxamide

Sources & evidence

ORD record
ord-130b632462a64e7493ca4349add30b42
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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