Toluene → Benzyl 4-formylpiperidine-1-carboxylate

HRID 962195Notes

Reaction equation

HRID 962195 reaction equation
[CH3:1][O:2][C:3](=[O:4])[CH:5]1[CH2:6][CH2:7][N:8]([C:11](=[O:12])[O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:9][CH2:10]1.[CH3:21][CH:22]([CH2:23][AlH:24][CH2:25][CH:26]([CH3:27])[CH3:28])[CH3:29].[CH3:30][c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1.[CH3:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42]>>[O:2]=[CH:3][CH:5]1[CH2:6][CH2:7][N:8]([C:11](=[O:12])[O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:9][CH2:10]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 8058HexaneHCID 14487Diisobutylaluminum hydrideHCID 15125441-Benzyl 4-methyl piperidine-1,4-dicarboxylate

Product 1

HCID 2776272Benzyl 4-formylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-e61ca56e962749efbbbe68fa5963c58b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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