Acetonitrile → 3-tert-Butyl 4-methyl 2,2-dimethyl-1,3-oxazolidine-3,4-dicarboxylate

HRID 962215Notes

Reaction equation

HRID 962215 reaction equation
[C:17](=[O:18])([O-:22])[O:23][C:19]([CH3:20])([CH3:21])[CH3:24].[C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])([O-:15])=[O:16].[CH3:1][O:2][C:3]([CH:4]([NH2:5])[CH2:6][OH:7])=[O:8].[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:32][C:33]#[N:34]>>[CH3:1][O:2][C:3]([CH:4]1[N:5]([C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:16])[C:19]([CH3:20])([CH3:21])[O:7][CH2:6]1)=[O:8]

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 8471TriethylamineHCID 416960Methyl DL-serinateHCID 4613278tert-Butyl carbonate2×

Product 1

HCID 51384973-tert-Butyl 4-methyl 2,2-dimethyl-1,3-oxazolidine-3,4-dicarboxylate

Sources & evidence

ORD record
ord-a4086de3223a45ea8f90f6a751ec62c2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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