Hydrochloric Acid → 4'-Hydroxy-4-biphenylcarbonitrile

HRID 962275Notes

Reaction equation

[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([C:13]#[N:14])[cH:15][cH:16]2)[cH:7][cH:8]1.[ClH:17].[cH:18]1[cH:19][cH:20][n:21][cH:22][cH:23]1>>[OH:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([C:13]#[N:14])[cH:15][cH:16]2)[cH:7][cH:8]1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 1049Pyridine

HCID 93892[1,1'-Biphenyl]-4-carbonitrile, 4'-methoxy-

Product 1

HCID 1406104'-Hydroxy-4-biphenylcarbonitrile

Sources & evidence

ORD record: ord-4327537e7a954e9bb7903791b2200f7f
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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