Triethylamine → Tert-butyl 2-[(methanesulfonyloxy)methyl]pyrrolidine-1-carboxylate

HRID 962298Notes

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:13][OH:14])[CH2:10][CH2:11][CH2:12]1.[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[CH3:22][S:23]([Cl:24])(=[O:25])=[O:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:13][O:14][S:23]([CH3:22])(=[O:25])=[O:26])[CH2:10][CH2:11][CH2:12]1

Participants

Reactant 3

HCID 8471Triethylamine

HCID 31297Methanesulfonyl chloride

HCID 550865tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 18007568Tert-butyl 2-[(methanesulfonyloxy)methyl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record: ord-a8fbdc83bfa44c919332bf0840d20d6a
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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