→ PROP-2-ENYL 1,6-DIMETHYL-4-(3-NITROPHENYL)-2-OXO-3,4-DIHYDROPYRIMIDINE-5-CARBOXYLATE

HRID 962326Notes

Reaction equation

HRID 962326 reaction equation
C=CCOC(=O)CC(C)=O.CC(=O)O.CCO.CNC(N)=O.O.O=Cc1cccc([N+](=O)[O-])c1.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.O=S(=O)([O-])C(F)(F)F.[Yb+3]>>C=CCOC(=O)C1=C(C)N(C)C(=O)NC1c1cccc([N+](=O)[O-])c1

Participants

7

Reactant 0

No Reactant data yet.

Product 1

HCID 2864830PROP-2-ENYL 1,6-DIMETHYL-4-(3-NITROPHENYL)-2-OXO-3,4-DIHYDROPYRIMIDINE-5-CARBOXYLATEYield 51%

Reagents, catalysts & solvents 6

HCID 176Acetic AcidOtherHCID 702EthanolOtherHCID 74493-NitrobenzaldehydeOtherHCID 11719MethylureaOtherHCID 70701Allyl acetoacetateOtherHCID 45075687Ytterbium(3+) trifluoromethanesulfonate--water (1/3/1)Other

Conditions

Temperature
120 °C

Workup

  1. waitNo procedure recorded
  2. additionNo procedure recorded
  3. waitNo procedure recorded
  4. filtrationKeep solid
  5. washNo procedure recorded
  6. dry in vacuumNo procedure recorded

Sources & evidence

ORD record
ord-4ab8bdf0768b47af91c578fe8d708887
Source dataset
Microwave-assisted Biginelli Condensation Dataset
Original link
View source

Reaction notes

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