HCID 19084735, compound → HCID 178525983, compound

Participants

Reaction Steps

A mixture of 2-Hydroxy-2-phosphono-4-(2-pyridylamino)butanoic acid (1.5 g), 100 ml of distilled water, and 0.5 g of palladium on carbon catalyst is hydrogenated at 40 PSI on a Parr apparatus for 2 days. The catalyst is removed by filtration, and the filtrate is evaporated to dryness under vacuum. The resulting crude product is purified by recrystallization from water/ethanol to yield 2-hydroxy-2-phosphono-4-((2-piperidinylidene)amino)butanoic acid.

Provenance & Evidence