Ethanethiol → HCID 19085083, compound

HRID 962416Notes

Reaction equation

HRID 962416 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[S:13][C:12]3[CH:14]=[C:15]([O:18]C)[CH:16]=[CH:17][C:11]=3[C:10]=2[C:20]([C:22]2[CH:31]=[CH:30][C:29]3[C:24](=[CH:25][CH:26]=[C:27]([O:32][CH2:33][CH2:34][N:35]4[CH2:40][CH2:39][CH2:38][CH2:37][CH2:36]4)[CH:28]=3)[CH:23]=2)=[O:21])=[CH:5][CH:4]=1.[Al+3].[Cl-].[Cl-].[Cl-].CCS>>[OH:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[S:13][C:12]3[CH:14]=[C:15]([OH:18])[CH:16]=[CH:17][C:11]=3[C:10]=2[C:20]([C:22]2[CH:31]=[CH:30][C:29]3[C:24](=[CH:25][CH:26]=[C:27]([O:32][CH2:33][CH2:34][N:35]4[CH2:36][CH2:37][CH2:38][CH2:39][CH2:40]4)[CH:28]=3)[CH:23]=2)=[O:21])=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 6343EthanethiolHCID 6451240Aluminum(III) ChlorideHCID 19085088HCID 19085088, compound

Product 1

HCID 19085083HCID 19085083, compoundYield 42.9%

Procedure

In a manner similar to that used in Example 2, 1.4 g (2.54 mmol) of [2-(4-methoxyphenyl)-6-methoxybenzo[b]thien-3-yl][6-[2-(1-piperidinyl)ethoxy]naphth-2-yl]methanone, 1.4 g (10.2 mmol) of AlCl3, and 2 mL (12.7 mmol) of EtSH was converted to 570 mg of the title compound as a yellow powder.

Sources & evidence

ORD record
ord-0c3e9e8c92c448479db1ca1b3e53935a
Source dataset
uspto-grants-1998_06
Patent number
US05760030

Reaction notes

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