HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanethiol → [2-(4-Hydroxyphenyl)-6-hydroxybenzo[b]thien-3-yl][6-[2-(1-piperidinyl)ethoxy]naphth-2-yl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanethiol | HCID 6343 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | HCID 19085088 | HCID 19085088 | — |
| Product | [2-(4-Hydroxyphenyl)-6-hydroxybenzo[b]thien-3-yl][6-[2-(1-piperidinyl)ethoxy]naphth-2-yl]methanone | HCID 19085083 | 42.9% |
Reaction Steps
In a manner similar to that used in Example 2, 1.4 g (2.54 mmol) of [2-(4-methoxyphenyl)-6-methoxybenzo[b]thien-3-yl][6-[2-(1-piperidinyl)ethoxy]naphth-2-yl]methanone, 1.4 g (10.2 mmol) of AlCl3, and 2 mL (12.7 mmol) of EtSH was converted to 570 mg of the title compound as a yellow powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05760030 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-0c3e9e8c92c448479db1ca1b3e53935a |
| Source note | uspto-grants-1998_06 |