HRID962923

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1=C(C(=O)OCCNC(=O)c2ccccc2C(=O)O)C(c2cccc([N+](=O)[O-])c2)C(C(=O)OCCNC(=O)c2ccccc2C(=O)O)=C(C)N1

HCID10930520

未命名化合物

PRODUCTS

生成物

结构：CC1=C(C(=O)O)[C@@H](c2cccc([N+](=O)[O-])c2)C(C(=O)OCCNC(=O)c2ccccc2C(=O)O)=C(C)N1

HCID10907345

未命名化合物

收率 41.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

To the culture liquor was added a solution of 100 mg of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl) pyridine-3,5-dicarboxylic acid bis[2-(2-carboxybenzoyl)aminoethyl] ester in 0.75 ml of deionized water, and shaked for continuous 2 days at 28° C. to obtain 30 mg of (4R)-1,4-dihydro-2,6-dimethyl-3-[2-(2-carboxybenzoyl) aminoethyl]oxycarbonyl-4-(3-nitrophenyl)pyridine-5-carboxylic acid by the same procedures as of Example 9.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-30165997c2324ee485df7570cc9987a8
来源数据集: uspto-grants-1998_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05760238
来源说明: uspto-grants-1998_06

反应 SMILES

C(C1C=CC=CC=1C(NCC[O:11][C:12]([C:14]1[CH:19]([C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([N+:26]([O-:28])=[O:27])[CH:21]=2)[C:18]([C:29]([O:31][CH2:32][CH2:33][NH:34][C:35](=[O:45])[C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][C:37]=2[C:42]([OH:44])=[O:43])=[O:30])=[C:17]([CH3:46])[NH:16][C:15]=1[CH3:47])=[O:13])=O)(O)=O>O>[CH3:46][C:17]1[NH:16][C:15]([CH3:47])=[C:14]([C:12]([OH:13])=[O:11])[C@@H:19]([C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([N+:26]([O-:28])=[O:27])[CH:21]=2)[C:18]=1[C:29]([O:31][CH2:32][CH2:33][NH:34][C:35](=[O:45])[C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][C:37]=1[C:42]([OH:44])=[O:43])=[O:30]