1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl) pyridine-3,5-dicarboxylic acid bis[2-(2-carboxybenzoyl)aminoethyl] ester → (4R)-1,4-dihydro-2,6-dimethyl-3-[2-(2-carboxybenzoyl) aminoethyl]oxycarbonyl-4-(3-nitrophenyl)pyridine-5-carboxylic acid

Participants

Reaction Steps

To the culture liquor was added a solution of 100 mg of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl) pyridine-3,5-dicarboxylic acid bis[2-(2-carboxybenzoyl)aminoethyl] ester in 0.75 ml of deionized water, and shaked for continuous 2 days at 28° C. to obtain 30 mg of (4R)-1,4-dihydro-2,6-dimethyl-3-[2-(2-carboxybenzoyl) aminoethyl]oxycarbonyl-4-(3-nitrophenyl)pyridine-5-carboxylic acid by the same procedures as of Example 9.

Provenance & Evidence