HCID 19085257, compound → HCID 19085172, compound

Participants

Reaction Steps

tert-Butyl 3-(3-(4-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-5-methyl[1,2,4]triazol-3-ylmethyl)ureido)phenylacetate (0.92 g) was dissolved in formic acid (20 ml), and the solution was allowed to stand at room temperature for one day. The reaction mixture was concentrated, and the obtained residue was recrystallized from ethyl acetate and isopropyl ether to give 0.66 g of 3-(3-(4-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-5-methyl[1,2,4]triazol-3-ylmethyl)ureido)phenylacetic acid.

Provenance & Evidence