HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (3-(2-Chlorobenzoyl)-2-(3-(2-indolecarbonylaminomethyl)-5-methyl[1,2,4]triazol-4-yl)thiophen-5-yl)carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 86752701 | HCID 86752701 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (3-(2-Chlorobenzoyl)-2-(3-(2-indolecarbonylaminomethyl)-5-methyl[1,2,4]triazol-4-yl)thiophen-5-yl)carboxylic acid | HCID 19085202 | 34.9% |
Reaction Steps
Ethyl (3-(2-chlorobenzoyl)-2-(3-(2-indolecarbonylaminomethyl)-5-methyl[1,2,4]triazol-4-yl)thiophen-5-yl)carboxylate (0.16 g) was hydrolyzed using a 2M aqueous sodium hydroxide solution (0.22 ml) and methanol (1 ml) to give 0.053 g of (3-(2-chlorobenzoyl)-2-(3-(2-indolecarbonylaminomethyl)-5-methyl[1,2,4]triazol-4-yl)thiophen-5-yl)carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05760032 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-c2feb367472f496ebc2ec88d1d48800d |
| Source note | uspto-grants-1998_06 |