HCID 19085144, compound → HCID 19085170, compound

Participants

Reaction Steps

tert-Butyl 3-(3-(4-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-5-methyl[1,2,4]triazol-3-ylmethyl)ureido)benzoate (800 mg) was dissolved in formic acid (20 ml), and the solution was allowed to stand for one day. The reaction mixture was concentrated, and the obtained crude crystals were recrystallized from isopropyl alcohol to give 580 mg of 3-(3-(4-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-5-methyl[1,2,4]triazol-3-ylmethyl)ureido)benzoic acid.

Provenance & Evidence