HCID 86752711, compound → HCID 67662575, compound

Participants

Reaction Steps

tert-Butyl 1-((4-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-5-methyl[1,2,4]triazol-3-yl)methylcarbamoylmethyl)indole-3-carboxylate (500 mg) was dissolved in formic acid (5 ml), and the solution was allowed to stand for one day. The reaction mixture was concentrated, and the obtained residue was crystallized from ethyl acetate to give 184 mg of 1-((4-(3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl)-5-methyl[1,2,4]triazol-3-yl)methylcarbamoylmethyl)indole-3-carboxylic acid.

Provenance & Evidence