Potassium Carbonate → HCID 11051953, compound

Participants

Reaction Steps

15 g (62.2 mmol) of 2-imino-3-(3-fluoropropyl)thiazoline hydrobromide (4: Z=Br) was dissolved in 150 ml of water, and 8.59 g (62.2 mmol) of anhydrous potassium carbonate was added. The mixture was stirred at room temperature for 10 minutes. The mixture was extracted with 150 ml of chloroform 4 times, and the organic layer was washed with saturated aqueous salt solution and dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure to obtain 9.45 g of 2-imino-3-(3-fluoropropyl)thiazoline (3) as an oily substance.

Provenance & Evidence