HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propyl p-toluenesulfonate → 1-[3-(5-Methylbenzo[b]furan-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)piperazine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propyl p-toluenesulfonate | HCID 69035 | — |
| Reactant | 1-(3-Methoxypyridin-2-yl)piperazine | HCID 12790495 | — |
| Reactant | 1-[3-(5-Chlorobenzo[b]furan-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)piperazine hydrochloride | HCID 19081494 | — |
| Product | 1-[3-(5-Methylbenzo[b]furan-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)piperazine hydrochloride | HCID 19081485 | — |
Reaction Steps
The title compound was prepared (0.66 g, 92%, mp 163°-165° C.) in a manner analogous to the preparation of 1-[3-(5-chlorobenzo[b]furan-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)piperazine (Example 25) by the reaction of 5-methyl-3-benzo[b]furan)propanol tosylate with 1-(3-methoxy-2-pyridinyl)piperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763444 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-1b090091b2304a45825244750973c446 |
| Source note | uspto-grants-1998_06 |