HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Methoxypyridin-2-yl)piperazine → 1-[3-(Benzo[b]furan-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)piperazine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Methoxypyridin-2-yl)piperazine | HCID 12790495 | — |
| Reactant | 3-Benzo[b]furanpropanol tosylate | HCID 19081457 | — |
| Reactant | 1-[3-(5-Chlorobenzo[b]furan-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)piperazine hydrochloride | HCID 19081494 | — |
| Product | 1-[3-(Benzo[b]furan-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)piperazine hydrochloride | HCID 19081445 | — |
Reaction Steps
The title compound was prepared (0.73 g, 91%, mp 179.5°-182° C.) in a manner analogous to the preparation of 1-[3-(5-chlorobenzo[b]furan-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)piperazine (Example 25) by the reaction of 3-benzo[b]furanpropanol tosylate with 1-(3-methoxy-2-pyridinyl)piperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05763444 |
| Source dataset | uspto-grants-1998_06 |
| ORD ID | ord-5828a24f62444aafb203045a973d505c |
| Source note | uspto-grants-1998_06 |