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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 963225Generated: October 26, 2026

1-(3-Methoxypyridin-2-yl)piperazine → HCID 19081513, compound

https://huagongshe.com/reaction/963225

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Methoxypyridin-2-yl)piperazineHCID 12790495—
Reactant5-Methoxy-3-benzo[b]furanpropanol tosylateHCID 19081430—
Reactant1-[3-(5-Methoxybenzo[b]furan-3-yl)propyl]-4-(5-methoxy-4-pyrimidinyl)piperazine hydrochlorideHCID 19081483—
ProductHCID 19081513HCID 19081513—

Reaction Steps

The title compound was prepared (0.69 g, 75%, mp 174°-176° C.) in a manner analogous to the preparation of 1-[3-(5-methoxybenzo[b]furan-3-yl)propyl]-4-(5-methoxy-4-pyrimidinyl)piperazine hydrochloride (Example 39) by the reaction of 5-methoxy-3-benzo[b]furanpropanol tosylate with 1-(3-methoxy-2-pyridinyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05763444
Source datasetuspto-grants-1998_06
ORD IDord-8367917f04db430abc03413c2770d17c
Source noteuspto-grants-1998_06