HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
p-Toluenesulfonate → 1-[3-(Benzo[b]thien-3-yl)propyl]-4-(5-methoxy-4-pyrimidinyl)-2-methylpiperazine hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | p-Toluenesulfonate | HCID 85570 | — |
| Edukt | 5-Methoxy-4-(3-methylpiperazin-1-yl)pyrimidine | HCID 15020545 | — |
| Edukt | 1-[3-(Benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride | HCID 19081472 | — |
| Produkt | 1-[3-(Benzo[b]thien-3-yl)propyl]-4-(5-methoxy-4-pyrimidinyl)-2-methylpiperazine hydrochloride | HCID 19081520 | — |
Reaktionsschritte
The title compound was prepared (0.80 g, 85%, mp 200°-205° C.) in a manner analogous to the preparation of 1-[3-(benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride (Example 41) by the reaction of 3-benzo[b]thienepropanol tosylate with 1-(5-methoxy-4-pyrimidinyl)-3-methylpiperazine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05763444 |
| Quelldatensatz | uspto-grants-1998_06 |
| ORD ID | ord-39fbc8458da54066b8c61746c8ec53e9 |
| Quellennotiz | uspto-grants-1998_06 |