Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Toluenesulfonate → 1-[2-(Benzo[b]thien-3-yl)ethyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Toluenesulfonate | HCID 85570 | — |
| 반응물 | 1-[3-(Benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride | HCID 19081472 | — |
| 반응물 | 1-(3-Methoxy-2-pyridinyl)-3-methylpiperazine | HCID 19081481 | — |
| 생성물 | 1-[2-(Benzo[b]thien-3-yl)ethyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride | HCID 19081492 | — |
반응 단계
The title compound was prepared (1.39 g, 85%, mp 197°-200° C.) in a manner analogous to the preparation of 1-[3-(benzo[b]thien-3-yl)propyl]-4-(3-methoxy-2-pyridinyl)-2-methylpiperazine hydrochloride (Example 41) by the reaction of 3-benzo[b]thieneethanol tosylate (Example 47) with 1-(3-methoxy-2-pyridinyl)-3-methylpiperazine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05763444 |
| 출처 데이터셋 | uspto-grants-1998_06 |
| ORD ID | ord-0aba6f5da7af44d6845fa935bdf913b4 |
| 출처 메모 | uspto-grants-1998_06 |