Water → 6-Fluoro-3-[4-(4-iodo-3-methoxy-phenyl)-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoro-ethyl)-1,3,4,5-tetrahydro-1-benzazepin-2-one
Reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[Cs+:32].[Cs+:33].[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[CH2:8][CH2:9][CH:10]([n:14]1[n:15][n:16][c:17](-[c:19]3[cH:20][c:21]([O:26][CH3:27])[c:22]([I:25])[cH:23][cH:24]3)[cH:18]1)[C:11](=[O:13])[NH:12]2.[F:34][C:35]([F:36])([F:37])[S:38]([O:39][CH2:40][C:41]([F:42])([F:43])[F:44])(=[O:45])=[O:46].[OH2:52]>>[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[CH2:8][CH2:9][CH:10]([n:14]1[n:15][n:16][c:17](-[c:19]3[cH:20][c:21]([O:26][CH3:27])[c:22]([I:25])[cH:23][cH:24]3)[cH:18]1)[C:11](=[O:13])[N:12]2[CH2:40][C:41]([F:42])([F:43])[F:44]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fe00af9a90d9450da540d2096a0e4669
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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