Methanol → N-[[3-[3-fluoro-4-[4-hydroxy-4-(piperazin-1-ylmethyl)piperidin-1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

HRID 96338Notes

Reaction equation

HRID 96338 reaction equation
[CH2:27]1[CH2:28][NH:29][CH2:30][CH2:31][NH:32]1.[CH3:33][OH:34].[O:1]1[CH2:2][C:3]12[CH2:4][CH2:5][N:6]([c:9]1[c:10]([F:26])[cH:11][c:12]([N:15]3[C:16](=[O:25])[O:17][CH:18]([CH2:20][NH:21][C:22]([CH3:23])=[O:24])[CH2:19]3)[cH:13][cH:14]1)[CH2:7][CH2:8]2>>[OH:1][C:3]1([CH2:2][N:29]2[CH2:28][CH2:27][NH:32][CH2:31][CH2:30]2)[CH2:4][CH2:5][N:6]([c:9]2[c:10]([F:26])[cH:11][c:12]([N:15]3[C:16](=[O:25])[O:17][CH:18]([CH2:20][NH:21][C:22]([CH3:23])=[O:24])[CH2:19]3)[cH:13][cH:14]2)[CH2:7][CH2:8]1

Participants

4

Reactant 3

HCID 887MethanolHCID 4837PiperazineHCID 72825524N-[[3-[3-fluoro-4-(1-oxa-6-azaspiro[2.5]octan-6-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Product 1

HCID 68700206N-[[3-[3-fluoro-4-[4-hydroxy-4-(piperazin-1-ylmethyl)piperidin-1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Sources & evidence

ORD record
ord-696b5aaf11614fc1822edc00b95013c2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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