Sodium ion → 2-(5,6-difluoro-2'-oxo-4'-pyrimidin-5-ylspiro[1-benzofuran-3,3'-indol]-1'(2' H)-yl)-N-(2-fluorophenyl)acetamide
Reaction equation
[Br:1][c:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[N:8]([CH2:22][C:23](=[O:24])[NH:25][c:26]1[c:27]([F:32])[cH:28][cH:29][cH:30][cH:31]1)[C:9](=[O:21])[C:10]21[CH2:11][O:12][c:13]2[c:14]1[cH:15][c:16]([F:20])[c:17]([F:19])[cH:18]2.[CH2:48]1[O:49][CH2:50][CH2:51][O:52][CH2:53]1.[CH3:54][CH2:55][O:56][C:57](=[O:58])[CH3:59].[Na+:42].[Na+:43].[O-:44][C:45](=[O:46])[O-:47].[cH:60]1[cH:61][cH:62][c:63]([P:64]([Pd:65]([P:66]([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)([P:85]([c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)[c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[P:104]([c:105]2[cH:106][cH:107][cH:108][cH:109][cH:110]2)([c:111]2[cH:112][cH:113][cH:114][cH:115][cH:116]2)[c:117]2[cH:118][cH:119][cH:120][cH:121][cH:122]2)([c:123]2[cH:124][cH:125][cH:126][cH:127][cH:128]2)[c:129]2[cH:130][cH:131][cH:132][cH:133][cH:134]2)[cH:135][cH:136]1.[n:33]1[cH:34][n:35][cH:36][c:37]([B:39]([OH:40])[OH:41])[cH:38]1>>[c:2]1(-[c:37]2[cH:36][n:35][cH:34][n:33][cH:38]2)[c:3]2[c:4]([cH:5][cH:6][cH:7]1)[N:8]([CH2:22][C:23](=[O:24])[NH:25][c:26]1[c:27]([F:32])[cH:28][cH:29][cH:30][cH:31]1)[C:9](=[O:21])[C:10]21[CH2:11][O:12][c:13]2[c:14]1[cH:15][c:16]([F:20])[c:17]([F:19])[cH:18]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-3b1c0d80a2c9416ab8a677a5d6946d9b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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